| S Club 7 Songs: Reach |
| Sade Songs: Your Love Is King · The Sweetest Taboo · Is It A Crime · No Ordinary Love · By Your Side |
| Sam The Sham & the Pharaohs Songs: Wooly Bully |
| Richard Sanderson Songs: Reality |
| Santa Esmeralda Songs: Don't Let Me Be Misunderstood |
| Santana |
| Songs: Smooth (with Rob Thomas) · Black Magic Woman · Oye Como Va · Maria Maria (with The Product G&B) |
| Santogold Songs: L.E.S. Artistes |
| Savage Garden Songs: To The Moon And Back · Truly Madly Deeply · I Knew I Loved You · Two Beds And A Coffee Machine · Affirmation |
| Leo Sayer Songs: When I Need You |
| Scissor Sisters Songs: I Don't Feel Like Dancin' |
| Scorpions Songs: Wind Of Change · Still Loving You |
| Jill Scott Songs: He Loves Me |
| Scouting for Girls Songs: She's So Lovely · Elvis Ain't Dead |
| Seal Songs: Kiss From A Rose · Love's Divine |
| The Searchers Songs: When You Walk In The Room |
| Selena Songs: Disco Medley - I Will Survive/Funky Town |
| Michael Sembello Songs: Maniac (Flashdance) |
| Shaggy Songs: Oh Carolina |
| Shakira Songs: Objection (Tango) · Whenever, Wherever · Underneath Your Clothes · Eyes Like Yours (Ojos Asi) · Don't Bother |
| The Shangri-Las Songs: Leader Of The Pack |
| Sandie Shaw Songs: Puppet On A String |
| Blake Shelton Songs: Some Beach |
| Vonda Shepard Songs: Searchin' My Soul (Ally McBeal) |
| Allan Sherman Songs: Hello Muddah! Hello Fadduh! |
| Shocking Blue Songs: Venus |
| Lucie Silvas Songs: Breathe In |
| Simon And Garfunkel Songs: Mrs. Robinson · Bridge Over Troubled Water · The Sound Of Silence · The Boxer |
| Carly Simon Songs: Nobody Does It Better (The Spy Who Loved Me) · Let The River Run (Working Girl) |
| Paul Simon Songs: 50 Ways To Leave Your Lover · Father And Daughter |
| Nina Simone |
| Songs: My Baby Just Cares For Me · Wild Is the Wind |
| Simple Plan Songs: Welcome To My Life · When I'm Gone · Untitled · Perfect |
| Simply Red Songs: Holding Back The Years · You Make Me Feel Brand New · Remembering The First Time |
| Ashlee Simpson Songs: Pieces Of Me · Boyfriend |
| Jessica Simpson Songs: These Boots Are Made For Walkin' · I Wanna Love You Forever · Take My Breath Away (Top Gun) |
| Frank Sinatra |
Francis Albert Sinatra (December 12, 1915 – May 14, 1998) was an American singer who is considered by ... Songs: Fly Me To the Moon (In Other Words) · My Way · New York, New York · Come Fly With Me · I've Got You Under My Skin |
| Nancy Sinatra |
| Songs: These Boots Are Made For Walking (Full Metal Jacket) |
| Bob Sinclar Songs: Love Generation |
| Sister Act |
| Songs: I Will Follow Him (Chariot) |
| Sister Act 2 |
Sister Act 2: Back in the Habit Songs: Oh Happy Day |
| Sister Sledge |
| Songs: We Are Family |
| Sixpence None the Richer Songs: Kiss Me (Dawson's Creek) · Don't Dream It's Over |
| Skunk Anansie |
| Songs: Hedonism (Just Because You Feel Good) |
| Lynyrd Skynyrd |
| Songs: Sweet Home Alabama |
| Sly And The Family Stone Songs: Dance To The Music |
| Millie Small |
| Songs: My Boy Lollipop |
| Smash Mouth Songs: I'm A Believer (Shrek) · All Star (Shrek) |
| Michael W. Smith Songs: Friends |
| Smokie Songs: Living Next Door To Alice |
| Snow Patrol |
Snow Patrol are a rock band from Scotland formed by Gary Lightbody, Paul Wilson, Jonny Quinn, Tom Simpson, ... Songs: Chasing Cars · Run |
| Soft Cell Songs: Tainted Love |
| Soggy Bottom Boys |
| Songs: I Am A Man Of Constant Sorrow (O Brother Where Art Thou) |
| Martin Solveig Songs: Madan (Exotic Disco Edit) |
| Sonny and Cher Songs: I Got You Babe |
| Spandau Ballet Songs: True · Gold |
| Jordin Sparks |
| Songs: Tattoo · No Air · This Is My Now |
| Sam Sparro |
| Songs: Black And Gold |
| Britney Spears |
| Songs: Everytime · I'm Not A Girl, Not Yet A Woman · Piece of Me · Sometimes · ...Baby One More Time |
| Regina Spektor Songs: Fidelity |
| Spice Girls Songs: Stop · Lady Is A Vamp · Mama · Naked |
| Spin Doctors Songs: Two Princes |
| Dusty Springfield |
| Songs: Son Of A Preacher Man · You Don't Have To Say You Love Me · I Only Want To Be With You · I Just Don't Know What To Do With Myself |
| Bruce Springsteen |
| Songs: Santa Claus is Comin' To Town · Dancing In The Dark · Born In The USA · Streets Of Philadelphia (Philadelphia) · Born To Run |
| Staind Songs: It's Been Awhile |
| Lisa Stansfield Songs: All Around The World |
| Stars on 54 |
Ultra Nate, Amber, Jocelyn Enriquez Songs: If You Could Read My Mind |
| Status Quo Songs: Rockin' All Over The World · Whatever You Want · Down Down |
| Steam Songs: Na Na Hey Hey (Kiss Him Goodbye) |
| Jevetta Steele |
| Songs: Calling You (Bagdad Café) |
| Gwen Stefani Songs: Sweet Escape (ft. Akon) · Hollaback Girl · Rich Girl |
| Steppenwolf Songs: Born To Be Wild |
| Steps Songs: Thank Abba For The Music (feat. Tina Cousins, Billie Piper, Cleopatra and B*Witched) |
| Stereophonics Songs: Dakota · Have A Nice Day |
| Steve Miller Band Songs: The Joker |
| Amii Stewart |
| Songs: Knock On Wood |
| Rod Stewart |
| Songs: Have I Told You Lately That I Love You · I Don't Want To Talk About It · Smile · Maggie May · The First Cut Is The Deepest |
| Sting |
| Songs: Brand New Day · Fields Of Gold · Fragile · Desert Rose · Englishman In New York |
| Angie Stone Songs: Wish I Didn't Miss You |
| Joss Stone Songs: You Had Me · L-O-V-E · Baby Baby Baby |
| Paul Stookey Songs: The Wedding Song |
| George Strait |
| Songs: I Cross My Heart |
| Stray Cats Songs: Rock This Town |
| Barbra Streisand |
| Songs: The Man I Love · Memory · Don't Rain On My Parade · Somewhere · As If We Never Said Goodbye |
| Ruben Studdard Songs: Flying Without Wings |
| El sueño de Morfeo Songs: Para toda la vida · Demasiado tarde |
| Sugababes |
| Songs: About You Now (radio edit) · Too Lost In You |
| Sugarland |
| Songs: Baby Girl · Something More |
| Donna Summer |
| Songs: She Works Hard For The Money · Last Dance · MacArthur Park |
| The Supremes Songs: Where Did Our Love Go · Stop! In The Name Of Love · You Can't Hurry Love |
| Survivor Songs: Eye Of The Tiger (From Rocky III) |
| Taylor Swift |
| Songs: Our Song · Should've Said No · Picture To Burn · Tim McGraw |
| Switchfoot |
| Songs: Dare You To Move |
| SWV Songs: Weak |
| System Of A Down Songs: Chop Suey! |